I'm sick and tired of having to take care of your brother just because he refuses to go out and find a job.
只是因为你弟弟不肯出去找工作就得我来照顾他,这真让我烦透了。
and without giving any consideration to the effects produced on the individuals and on their descendants by the artificial mode of existence imposed by the factory.
工厂把一种人为的生存方式强加给工人,却不顾及这种生存方式给工人及其后代带来的影响。